In collaboration with the Clinic for Psychiatry and Psychotherapy and the Institute of Pharmacology and Toxicology in Tübingen, we recently published our study about the effects of daily Lithium injection in glutamine synthetase (GS) activity in mouse hippocampus. Thanks to our reporter mice, we were able to detect rapid changes in GS promotor activity. Turns out, daily Lithium injection might act protectively against injection stress by preventing stress-related GS-promotor activity changes found in control animals.
Thanks to the fortüne – Forschungsförderung der Tübinger Medizinischen Fakultät for funding this interesting project!
Check out our paper:
Lithium and glutamine synthetase: Protective effects following stress in Psychiatry Res. 2019 Aug;281:112544