The pandemic has been with us for over one year and but we have to go on. We are all the more pleased that Alesja Radini was able to succsessfully complete her bachelor thesis with us. She submitted her work with the title “Neurobiological correlates of mania- and depression- like behavior in the guanylyl- cyclase knock- out mouse” in April.
Month: April 2021
Successful establishment of our animal model for bipolar disorder in Bochum
In our new published study Prefrontal dopamine D1 receptor manipulation influences anxiety behavior and induces neuroinflammation within the hippocampus Dominik, Nadja and Annika investigated the effects of dopamine D1 receptor (D1R) over-expression and its termination on anxiety and the inflammatory state within the hippocampus. Interestingly, termination of D1R over-expression resulted in increased anxiety and inflammation. In addition, anxiety as well as inflammatory state correlated positively.
Find out more about the study here (link: https://pubmed.ncbi.nlm.nih.gov/33683478/)