DGBS Annual Conference in 2021

IMG20210925140317(1)From 23 September to 25 September 2021, the 20th DGBS Annual Conference took place in Heilbronn. In 2019, Prof. Dr. Nadja Freund was awarded the Jules Angst Research Prize as a young scientist in the field of bipolar disorder. In 2020, no annual meeting took place due to the pandemic. This year, Kirsten Schmerder was honored to give a lecture entitled “Does sleep deprivation make us sick? A study of photoperiod lengths manipulation in mice” as a speaker.

The next DGBS Annual Conference will take place from 15.09. – 17.09.2022 in Frankfurt am Main.  Hope to see you there!

Two in one fell swoop

Karina Violou and Selina Wagner were able to successfully complete their master’s thesis in our working group. Karina completed her master’s thesis entitled “Immune response during developement and its impact on mental health” in July 2021 and Selina Wagner was able to write her master’s thesis entitled “Investigation of neurobiological consequences of early life stress in the rat animal model” in August 2021. We congratulate both of them on this success and wish them all the best for their future.

Defense via ZOOM

DavidToday we can rejoice with David Wegrzyn. He successfully defended his P.hD. thesis entitled “In vitro analysis of the synaptogenesis and the formation of perineuronal nets in the Poly I:C mouse model considering the role of activated microglia“. His defense took place via ZOOM due to the pandemic, but he also mastered this hurdle confidently. We are proud of his achievement and congratulate him warmly. All the best for your future David.

The junior scientists

baby-shoes-1514007_1920Not only professionally but also in our private life fantastic things happened.
Prof. Dr. Nadja Freund pioneered in July 2019 and gave birth to little Keno. In October 2020 Dominik Beyer followed her in becoming parent when his son Florentin was born. Just four months later, in February 2021, Prof. Dr. Martina Mann’s became grandmother to little Linnea. In March 2021, Emma Maria was born, making Jennifer Koch a proud mum.
Last but not least, in May 2021 David became father to little Sophie. We wish the parents all the best. The next generation of young scientists is assured.


Covid-19 Update 2021

Covid-19 will be with us for this year and maybe beyond. Our laboratory is trying to make the best out of the situation. We continue organizing research and teaching our students as best as we can. On-site work at our laboratories continues follwing Corona specific rules like self-testing, distance, masks etc. continues as well as online meetings and remote office. 2020 taught us we can work together as a team in tough situations. We took our place in the fight against the Covid-19 pandemic. Members of the work group supported the LWL- University clinic in giving vaccines to employees. Future outlook is positively (at least rather negatively). We hope everything will be fine soon. Stay safe- stay healthy.

Congratulations Alesja

WhatsApp Image 2022-04-26 at 10.11.03The pandemic has been with us for over one year and but we have to go on. We are all the more pleased that Alesja Radini was able to succsessfully complete her bachelor thesis with us. She submitted her work with the title “Neurobiological correlates of mania- and depression- like behavior in the guanylyl- cyclase knock- out mouse” in April.

Successful establishment of our animal model for bipolar disorder in Bochum

brainIn our new published study Prefrontal dopamine D1 receptor manipulation influences anxiety behavior and induces neuroinflammation within the hippocampus Dominik, Nadja and Annika investigated the effects of dopamine D1 receptor (D1R) over-expression and its termination on anxiety and the inflammatory state within the hippocampus. Interestingly, termination of D1R over-expression resulted in increased anxiety and inflammation. In addition, anxiety as well as inflammatory state correlated positively.

Find out more about the study here (link: https://pubmed.ncbi.nlm.nih.gov/33683478/)

Welcome back

WhatsApp Image 2021-05-25 at 11.30.50We are very pleased to welcome Florian Rehrmann and Kirsten Schmerder back to our group. After Florian successfully completed his master’s thesis in our laboratory in 2020, he is now back as replace for Jennifer Koch during her maternity leave. We couldn’t ask for a better one for these tasks, as Florian got to know the laboratory and the processes very well during his master’s thesis.
Kirsten also successfully completed her master’s thesis with us in 2020 and is now returning to our work group as a doctoral candidate. During her PhD, she will continue her research and hopefully deepen our knowledge about neurobiological processes during depressive and manic episodes in bipolar disorder models. She will implement optogenetic approaches to be able to interfere with the dopaminergic system during behavioral assessment.
We are looking forward working together (again).


Goodbye Anna and Jennifer

This year we will have to say goodbye to Anna Mundorf, (transiently) to Jennifer Koch.
Anna successfully defended her Ph.D. in October 2020 and from March 2021 on, she will take up a position as a research assistant at the Medical School Hamburg (MSH).We wish you all the best and good luck in your future life.
Anna’s further professional career at MSH can be followed at this link:

Jennifer is our technical manager and is on maternity leave and will be on parental leave for one year. We will miss her, but we wish her all the best and a great time getting to know her baby.

Practical course in our group

WhatsApp Image 2020-12-04 at 11.54.51From 11/16/20 to 11/27/20 the practical course “Neurobiological visualization of social interaction in mice” took place in our group.
During this time, two students were able to conduct behavioral tests and record ultrasonic vocalizations under supervision. They also got an insight into the corresponding evaluation software. Tissue samples were taken from the animals and sections made with the cryostat. Immunohistological staining was carried out with subsequent photo documentation at the microscope.
This all-around insight into animal research will be given to two more trainees on December 7th, 2020.